My picks to come out of each region are Duke over Sparty in the east. Michigan over Gonzaga in the west. The south is the hardest region to pick because so many of the top seeds have a history of early exits. I think I'm going with Wisconsin over Villanova in the south. In the midwest, I'll take UNC over Kentucky.
In the Final Four, I'll go with Michigan over Duke and UNC over Wisconsin and in the title game, I'll take UNC over Michigan and Roy announces his retirement after the season.